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  • Title: Antimicrobial studies, synthesis and characterization of novel 1-nitro-10H-phenothiazine bearing sulfone/nucleoside moieties.
    Author: Jangid DK, Guleria A, Gautam DC, Yadav H, Mathur M, Swami AK.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2019; 38(8):533-549. PubMed ID: 30857466.
    Abstract:
    The current research article involves one pot synthesis of novel substituted 1-nitro-10H-phenothiazines via Smiles rearrangement. These substituted phenothiazines undergo oxidation to yield 10H-phenothiazine-5,5-dioxides (sulfones) while on treatment with β-D-ribofuranose-1-acetate-2,3,5-tribenzoate yield ribofuranosides. These compounds were screened for their antimicrobial vitalities (in vitro) against selected strains of bacteria and fungi. The characterization of synthesized compounds was done by elemental and spectral studies.
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