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  • Title: In Vitro Activities of Omadacycline against Rapidly Growing Mycobacteria.
    Author: Shoen C, Benaroch D, Sklaney M, Cynamon M.
    Journal: Antimicrob Agents Chemother; 2019 May; 63(5):. PubMed ID: 30858221.
    Abstract:
    The in vitro activity of omadacycline, a new tetracycline derivative, was evaluated against isolates of Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum using a broth microtiter dilution assay. Omadacycline had MIC90 values of 2 μg/ml, 0.25 μg/ml, and 0.5 μg/ml, respectively. The in vitro activity of omadacycline against rapidly growing mycobacteria indicates that it may have the potential to improve therapy for infections caused by these organisms.
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