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  • Title: [Antigenic study of the differentiation of the human kidney using monoclonal antibodies].
    Author: Candelier JJ, Couillin P, Eydoux P, Boué A.
    Journal: C R Acad Sci III; 1986; 302(8):303-8. PubMed ID: 3085884.
    Abstract:
    The production of monoclonal antibodies against human embryonic renal cells allowed to display on the adult human kidney some antigens typical of certain structures or tissues: the proximal convoluted tubule for EG 9-11 and EG 19-6 monoclonal antibodies, the glomerular basement membrane for EG 14-1, the urothelium for EE 24-6, the connective tissue for EK 8-1 and EK 17-1 and probably the capsular and tubular basement membranes for EK 8-1. Simultaneously, we could follow the spatial and temporal repartition of the antigens during the renal development. One of them (EI 16-1) seemed to disappear in the adult and might correspond to a foetal type-antigen.
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