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  • Title: [Effect of newborn rat testes on the male sexual behavior of the testosterone-treated adult].
    Author: Roffi J, Chami F, Corbier P.
    Journal: C R Acad Sci III; 1986; 302(12):467-70. PubMed ID: 3087592.
    Abstract:
    Neonatal male rats were castrated either at 0, 6 or 24 hrs. after birth. As adults, testosterone was delivered by subcutaneous implantation of a Silastic capsule containing this hormone. The probability to display mounting behavior in presence of an estrous female was lower when the animals were castrated at 0 hr. than at 6 or 24 hrs. or when they received a subcutaneous injection of 1 microgram of testosterone propionate, at the time of castration at 0 hr. These results suggest that in the rat, during the 6 hrs. following birth, neonatal testes influence the sensitivity of the adult central nervous system to testosterone.
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