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  • Title: H3K27M-Positive Primary Spinal Glioblastoma Presenting with Hemorrhage-A Rare Clinical Entity.
    Author: Uppar A, Konar SK, B N N, Shukla D.
    Journal: World Neurosurg; 2019 Jun; 126():223-227. PubMed ID: 30876988.
    Abstract:
    BACKGROUND: Primary spinal glioblastoma multiforme is a rare and aggressive spinal tumor with dismal outcomes CASE DESCRIPTION: We have presented an unusual case-the first, to the best of our knowledge, to be reported-with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay. CONCLUSION: The tumor was positive for histone molecular alteration, H3K27M.
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