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  • Title: Guanabenz as inhibitor of copper-containing amine oxidases.
    Author: Banchelli G, Bertocci B, Raimondi L, Soldani G, Del Tacca M, Buffoni F.
    Journal: Agents Actions; 1986 Apr; 18(1-2):46-8. PubMed ID: 3088929.
    Abstract:
    The effects of guanabenz on some copper containing amine oxidases are described. Guanabenz 'in vitro' inhibits pig plasma benzylamine oxidase with a IC50 M 5.1 +/- 0.8 X 10(-6) M. It also inhibits pig kidney diamine oxidase and rat liver mitochondrial monoamine oxidase at higher concentrations. The significance of this property of guanabenz is discussed.
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