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  • Title: RETRACTED: MicroRNA-34 suppresses proliferation of human ovarian cancer cells by triggering autophagy and apoptosis and inhibits cell invasion by targeting Notch 1.
    Author: Jia Y, Lin R, Jin H, Si L, Jian W, Yu Q, Yang S.
    Journal: Biochimie; 2019 May; 160():193-199. PubMed ID: 30905732.
    Abstract:
    This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editors. The substance of the retraction is as follows: Attention has been drawn by Dr Elisabeth Bik to the fact that similar images representing the results of different experiments are shown in Figures 1G and 3F. She also points to the remarkable similarity between the legend text and line graphs of Figure 1 of the Biochimie article, Jia et al (2019), and Figure 1 of a publication in Eur Rev Med Pharmacol Sci (2019), Xu et al (2019). The latter article has since been retracted. An anomymous reader has observed that Figures 1G and 3F show three rows of images shared with Figure 4 of the first-published version of a manuscript in the Journal of the Balkan Union of Oncology (J BUON), Tan et al (2019), submitted and accepted for publication before the submission of the Biochimie article, though it has since publication undergone unexplained modification to Figure 4. Furthermore, the panels shared between the Biochimie and J BUON articles are similar to panels in Figure 7 of a much earlier manuscript, published in October 2017 in Science Reports (Dai et al), as well as to a figure in a later article, Li et al (2020). In addition, the top panel of Figure 3G in Jia et al (2019) as well as the two lower panels is also similar to a part of Figure 7, Dia et al (2017). Further unexplained anomalies concern Figure 3C of Jia et al (2019). The editors would like to thank Dr Bik and the anonymous reader for their valuable insight in this matter. The above observations cast serious doubt on the scientific integrity of the Biochimie article. Confronted with the observation that panels in Figures 1G and 3F were similar though representing different experiments, the authors replied to the editors that the bottom panel in Figure 3F was a mistake and would be corrected. They were not able to produce the raw data when requested, and proposed to the editors to repeat the experiments. However, no new data have been received by the editors at the time of writing, and would not change the serious doubts that they harbour concerning the integrity of the work published in Biochimie. Therefore, the editorial team has opted for retraction irrespective of any new results. This decision has been accepted by the authors.
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