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Title: Inhibition of muscle glycogen phosphorylase b by vitamin B2 and its coenzyme forms. Author: Klinov SV, Kurganov BI, Pekel ND, Berezovskii VM. Journal: Biochem Int; 1986 Jul; 13(1):139-45. PubMed ID: 3092825. Abstract: Kinetic studies have demonstrated that vitamin B2 and its coenzyme forms FMN and FAD are potent inhibitors of glycogen phosphorylase b from rabbit skeletal muscle. The inhibition of the enzyme by flavins has a co-operative character (Hill coefficients exceed unity). Glycogen phosphorylase b bound to FMN or FAD does not reveal catalytic activity, whereas the enzyme bound to riboflavin retains about 16% of the initial catalytic activity.[Abstract] [Full Text] [Related] [New Search]