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  • Title: Enterocolic lymphocytic phlebitis with marked myointimal hyperplasia and perivenous concentric fibrosis.
    Author: Nakaya M, Hashimoto H, Nagata R, Usui G, Kusakabe M, Harihara Y, Horiuchi H, Yao T, Morikawa T.
    Journal: Cardiovasc Pathol; 2019; 40():68-71. PubMed ID: 30928813.
    Abstract:
    Enterocolic lymphocytic phlebitis (ELP) is a rare enteropathy characterized by lymphocytic phlebitis of the mesenteric veins without arteritis. Idiopathic myointimal hyperplasia of mesenteric veins (IMHMV) is a rare disease similar to ELP, characterized by myointimal hyperplasia that constricts the lumen of veins, causing mucosal injury. A 62-year-old man with chief complaint of abdominal pain was treated by partial resection of the ileum after 3 months of conservative therapy. The pathologic diagnosis was ELP with prominent myointimal hyperplasia. Histologically, the lesion consisted of lymphocytic infiltration into the vein accompanied by prominent myointimal hyperplasia and perivenous concentric fibrosis, which are characteristics shared by ELP and IMHMV. The observations in this case suggest that some of ELP and IMHMV may belong to the same disease spectrum. Furthermore, perivascular concentric fibrosis was a remarkable observation that may contribute to differential diagnosis between ELP and "true" IMHMV.
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