These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Smoke-Isolated Karrikins Stimulated Tanshinones Biosynthesis in Salvia miltiorrhiza through Endogenous Nitric Oxide and Jasmonic Acid.
    Author: Zhou J, Xu ZX, Sun H, Guo LP.
    Journal: Molecules; 2019 Mar 29; 24(7):. PubMed ID: 30934811.
    Abstract:
    Although smoke-isolated karrikins (KAR₁) could regulate secondary metabolism in medicinal plants, the signal transduction mechanism has not been reported. This study highlights the influence of KAR₁ on tanshinone I (T-I) production in Salvia miltiorrhiza and the involved signal molecules. Results showed KAR₁-induced generation of nitric oxide (NO), jasmonic acid (JA) and T-I in S. miltiorrhiza hairy root. KAR₁-induced increase of T-I was suppressed by NO-specific scavenger (cPTIO) and NOS inhibitors (PBITU); JA synthesis inhibitor (SHAM) and JA synthesis inhibitor (PrGall), which indicated that NO and JA play essential roles in KAR₁-induced T-I. NO inhibitors inhibited KAR₁-induced generation of NO and JA, suggesting NO was located upstream of JA signal pathway. NO-induced T-I production was inhibited by SHAM and PrGall, implying JA participated in transmitting signal NO to T-I accumulation. In other words, NO mediated the KAR₁-induced T-I production through a JA-dependent signaling pathway. The results helped us understand the signal transduction mechanism involved in KAR₁-induced T-I production and provided helpful information for the production of S. miltiorrhiza hairy root.
    [Abstract] [Full Text] [Related] [New Search]