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  • Title: On the nature of cellular ADP-ribosyltransferase from rat liver specific for elongation factor 2.
    Author: Sayhan O, Ozdemirli M, Nurten R, Bermek E.
    Journal: Biochem Biophys Res Commun; 1986 Sep 30; 139(3):1210-4. PubMed ID: 3094526.
    Abstract:
    A cellular ADP-ribosyltransferase, specific for elongation factor 2 (EF-2), is found in extracts from rat liver. Co-migrating with EF-2 throughout purification, this activity is, moreover, located in the protein bands corresponding to EF-2 after native or sodium dodecyl sulfate polyacrylamide gel electrophoresis. The observed activity is thus implicated to be an inherent property of EF-2. Preincubation of EF-2 with GuoPPCH2Pox inhibits endogenous, but not diphtheria toxin catalyzed ADP-ribosylation.
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