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  • Title: A new solid-phase assay for biotin and biocytin and its application to the study of patients with biotinidase deficiency.
    Author: Chan PW, Bartlett K.
    Journal: Clin Chim Acta; 1986 Sep 15; 159(2):185-96. PubMed ID: 3095002.
    Abstract:
    New solid-phase assays for the determination of biotin in plasma and urine and the determination of biocytin/biotinyl peptides in urine are described. These assays were used to demonstrate that patients with biotinidase deficiency excrete increased amounts of biocytin/biotinyl peptides.
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