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  • Title: Aqueductal stenosis as isolated localization involving the central nervous system in children affected by von Recklinghausen disease.
    Author: Spadaro A, Ambrosio D, Moraci A, Conforti R, Albanese V.
    Journal: J Neurosurg Sci; 1986; 30(1-2):87-93. PubMed ID: 3095508.
    Abstract:
    The Authors report three cases of non tumoral aqueductal stenosis associated with von Recklinghausen disease in children. Moreover, 16 similar cases collected from the literature are illustrated. The clinical features are evaluated in light of literature's data. Among all 19 cases, the median age was 19 years (range 6-46 years) and 9 patients were under the age of 13 years. In this latter group, the most represented clinical symptoms were headache and gait disturbances. As regards the neuroradiological procedures, CT scan represented the best tool in the evaluation of the ventricular size. Our own three cases underwent to ventriculo-atrial shunt procedures, followed by clinical recovery (follow-up: 3 months-5 years). In conclusion it is felt that, among all the pathological events usually described in patients affected by neurofibromatosis, aqueductal stenosis seems to belong to the natural history of this disease.
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