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  • Title: [Long-duration insomnia after lesions of the perikaryons of the paramedian preoptic area in cats].
    Author: Sallanon M, Kitahama K, Denoyer M, Gay N, Jouvet M.
    Journal: C R Acad Sci III; 1986; 303(10):403-9. PubMed ID: 3096502.
    Abstract:
    The destruction of paramedian preoptic neurons by intra-tissue injection of ibotenic acid induces, in the cat, the disappearance of deep slow wave sleep and paradoxical sleep for 2 to 4 weeks, while light slow wave sleep is slightly disturbed. This insomnia, well tolerated, is not secondarily associated with central temperature disturbance.
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