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  • Title: Dedicated monitoring of anesthetic and respiratory gases by Raman scattering.
    Author: VanWagenen RA, Westenskow DR, Benner RE, Gregonis DE, Coleman DL.
    Journal: J Clin Monit; 1986 Oct; 2(4):215-22. PubMed ID: 3097268.
    Abstract:
    The monitoring of respiratory and anesthetic gases in the operating room is important for patient safety. This study measured the accuracy and response time of a multiple-gas monitoring instrument that uses Raman light scattering. Measurements of oxygen, carbon dioxide, nitrogen, nitrous oxide, halothane, enflurane, and isoflurane concentrations were compared with a gas mixer standard and with measurements made with an infrared anesthetic agent analyzer. Correlation coefficients were all greater than 0.999, and probable errors were less than 0.43 vol% for the gases and less than 0.03 vol% for the volatile anesthetics. Response time was 67 ms with a sample flow rate of 150 ml/min. There was some signal overlap between nitrogen and nitrous oxide and between the volatile anesthetic agents. Such overlap can be compensated for by linear matrix analysis. The Raman instrument promises a monitoring capability equivalent to the mass spectrometer and should prove attractive for the monitoring of respiratory and anesthetic gases in the operating room.
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