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  • Title: Inhibition of vitamin A action in rat bone cultures by inhibitors of RNA and protein synthesis.
    Author: Kistler A.
    Journal: Experientia; 1978 Sep 15; 34(9):1159-61. PubMed ID: 309826.
    Abstract:
    Using explanted humeri of late fetal rats, retinoic acid induced a dose- and time-dependent regression of cartilage. The retinoic acid-induced release of proteoglycan into the medium was blocked by inhibitors of RNA and protein synthesis, suggesting its dependence upon continuous RNA and protein synthesis.
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