These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Lipid peroxidation in regenerating rat liver.
    Author: Cheeseman KH, Collins M, Maddix S, Milia A, Proudfoot K, Slater TF, Burton GW, Webb A, Ingold KU.
    Journal: FEBS Lett; 1986 Dec 15; 209(2):191-6. PubMed ID: 3098579.
    Abstract:
    Rats entrained to a strictly regulated lighting and feeding schedule have been subjected to partial hepatectomy or a sham operation. In the partially hepatectomised animals the period of liver regeneration is characterised by regular bursts of thymidine kinase activity. Liver microsomes from rats, at times corresponding to maximum thymidine kinase activity, have much reduced rates of lipid peroxidation compared to control preparations: this is due in part to increased levels of lipid-soluble antioxidant at times of maximal DNA synthesis. This temporal relationship between thymidine kinase and lipid peroxidation is consistent with the view that lipid peroxidation is decreased prior to cell division.
    [Abstract] [Full Text] [Related] [New Search]