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  • Title: Size-controlled DNA-cross-linked hydrogel coated silica nanoparticles served as a ratiometric fluorescent probe for the detection of adenosine triphosphate in living cells.
    Author: Ji X, Wang J, Niu S, Ding C.
    Journal: Chem Commun (Camb); 2019 May 08; 55(36):5243-5246. PubMed ID: 30989156.
    Abstract:
    Herein, we have designed a ratiometric fluorescent nanoprobe for adenosine triphosphate sensing and imaging in living cells, based on silica nanoparticles and a DNA-functionalized hybrid hydrogel. This ratiometric detecting method could validly avoid false-positive signals. Due to its controllable size, favorable biocompatibility and biostability, the nanohydrogel exhibited high cellular permeability and fast response in living cells.
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