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Title: A highly selective and sensitive dual-mode sensor for colorimetric and turn-on fluorescent detection of cyanide in water, agro-products and living cells. Author: Guo Z, Niu Q, Yang Q, Li T, Chi H. Journal: Anal Chim Acta; 2019 Aug 13; 1065():113-123. PubMed ID: 31005143. Abstract: A new highly selective and sensitive dual-mode sensor 3TD based on the conjugate of oligothiophene and barbituric acid moiety was developed for colorimetric and turn-on fluorescent detection of CN─. The sensor 3TD exhibited high specificity towards CN─ by interrupting its own ICT producing thereupon a large blue-shift in UV-Vis spectrum and remarkable "turn-on" fluorescence emission. The detection limit was 2.26 × 10─7 M, which is quite lower than the permissible level of CN─ in drinking water according to the WHO. The fluorescent detection of CN─ was well demonstrated by filter paper strips and silica coated TLC plates. Moreover, the sensor was also used to detect CN─ in environmental water and agro-products with satisfactory results. Most importantly, in terms of these advantages of colorimetric and turn-on fluorescent dual-mode, immediate response, excellent selectivity, high sensitivity, low cytotoxicity, and good biocompatibility, the sensor 3TD was successfully applied into CN- imaging in living cells, demonstrating its excellent value in practical application.[Abstract] [Full Text] [Related] [New Search]