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  • Title: Immunological features of kala-azar.
    Author: Rezai HR, Ardehali SM, Amirhakimi G, Kharazmi A.
    Journal: Am J Trop Med Hyg; 1978 Nov; 27(6):1079-83. PubMed ID: 310248.
    Abstract:
    Serum immunoglobulins, complement C3c, percentage of T and B cells, and skin reactivity to Leishmania were studied in ten cases of kala-azar. Immunoglobulin G was increased in a majority of these patients. The C3c level in two out of six patients tested was lower than normal. The percentage of T cells in peripheral blood of nine patients tested was reduced and in seven of these patients the percentage of B cells was elevated. After a full course of anti-kala-azar therapy the percentage of T and B cells remained the same in five patients studied. All the patients showed a negative skin reaction when they were tested with Leishmania antigen.
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