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  • Title: Limitations in the use of indium-111-oxine-labeled leucocytes for the diagnosis of occult infection in children.
    Author: Haentjens M, Piepsz A, Schell-Frederick E, Perlmutter-Cremer N, Frühling J.
    Journal: Pediatr Radiol; 1987; 17(2):139-42. PubMed ID: 3104871.
    Abstract:
    Fifteen children underwent scintigraphy with indium 111 (111In)-labeled white blood cells (WBC) for the detection of a local suppuration. The procedure generally contributed to a correct diagnosis. False negative results were observed in 5 children, but in two of them positive foci were also present. The missed lesions were 2 liver abscesses, 1 lung abscess, foci of osteomyelitis and 1 pericarditis. Two cases of chronic granulomatous disease are presented in which increased leucocyte accumulation was not observed in proven instances of infection.
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