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Title: In vitro susceptibility of gram-positive cocci to paldimycin. Author: Pohlod DJ, Saravolatz LD, Somerville MM. Journal: Antimicrob Agents Chemother; 1987 Jan; 31(1):104-7. PubMed ID: 3105438. Abstract: Paldimycin (U-70138F) is a new antimicrobial agent with activity against gram-positive cocci. Clinical isolates of staphylococci and streptococci were tested. MICs were higher in Mueller-Hinton broth than in nutrient broth. Change in pH had minimal effect on the MICs in either broth. When inoculum size was varied, an inoculum effect was observed. The gram-positive cocci tested were generally more susceptible to paldimycin than to vancomycin.[Abstract] [Full Text] [Related] [New Search]