These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Perylene diimide-functionalized CeO2 nanocomposite as a peroxidase mimic for colorimetric determination of hydrogen peroxide and glutathione.
    Author: Lian J, Liu P, Jin C, Shi Z, Luo X, Liu Q.
    Journal: Mikrochim Acta; 2019 May 06; 186(6):332. PubMed ID: 31062174.
    Abstract:
    A novel perylene diimide (PDI) functionalized CeO2 nanocomposite (NC) was successfully fabricated via one-pot hydrothermal method. Compared with pure CeO2 nanoparticles (CeO2 NPs), the NC catalyst presents more Ce3+ and active oxygen species and exhibits a higher peroxidase mimicking activity towards the oxidation 3,3',5,5'-tetramethylbenzidine by H2O2 to form a blue product with an absorption maximum at 652 nm. The composite catalyst shows high sensitivity and selectivity toward H2O2 determination in the range of 20 to 80 μM with a limit of detection (LOD) of 2.59 μM. Based on the colorimetric method, a sensitive method for detecting the reduced glutathione (GSH) was also established over arrange of 1~4 μM with a LOD of 0.92 μM. Electron spin resonance (ESR) experiments suggest that the active radicals during the catalytic processes are •OH and •O2-. A possible synergistic catalytic mechanism is discussed. Graphical abstract Schematic presentation of the possible catalytic mechanism for colorimetric determination of hydrogen peroxide and glutathione based on the peroxidase-like activity perylene-diimide (PDI) functionalized CeO2 nanocomposite.
    [Abstract] [Full Text] [Related] [New Search]