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  • Title: Subungual Melanoma.
    Author: Littleton TW, Murray PM, Baratz ME.
    Journal: Orthop Clin North Am; 2019 Jul; 50(3):357-366. PubMed ID: 31084838.
    Abstract:
    Subungual melanoma is a rare form of melanoma that presents a unique set of challenges largely based on the complex anatomy of the nail unit. Subungual melanoma often first appears with longitudinal melanonychia. Thus, practitioners must have a high clinical suspicion in any patient with longitudinal melanonychia and a low threshold for a biopsy. The "ABCDEF" guide can be a useful tool to aid in screening any lesion of the nail bed. The authors recommend that biopsies of the nail unit be performed by a surgeon with an in-depth understanding of the pathoanatomy of subungual melanoma.
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