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  • Title: [Retrograde vascular catheterization as a differential diagnostic method of studying androgenization in the female].
    Author: Seifert B, Boehlke R, Fröhlich R, Seliger E, Nickel I.
    Journal: Zentralbl Gynakol; 1987; 109(8):487-92. PubMed ID: 3111127.
    Abstract:
    In 20 women with marked androgynism or testosterone concentrations being suspected for a tumor blood samples were taken by selective retrograde catheterization of the ovarian and suprarenal veins via vena femoralis. Testosterone, 17 beta-estradiol, and progesterone were determined and the concentration gradients to peripheral blood levels were calculated. In 20% of patients an pure adrenal and in 5% an ovarian hypersecretion of testosterone was established. A combined adrenal-ovarian hypersecretion was found in 50%. In 25% of the cases no final estimation was made because anatomic variations in venous size and drainage made catheterization and bilateral blood sampling impossible. There were no references to an androgen-secreting tumor.
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