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  • Title: Eleven New Triterpenoid Glycosides from the Roots of Ilex asprella.
    Author: Huang XJ, Wen S, Guan XF, Wu ZL, Li MM, Fan CL, Zhang QW, Chan G, Wang Y, Ye WC.
    Journal: Chem Biodivers; 2019 Jul; 16(7):e1900202. PubMed ID: 31115136.
    Abstract:
    Asprellosides A-K, nine new ursane-type triterpenoid glycosides (1-9), and two new oleanane-type triterpenoid glycosides (10 and 11), including six rare sulfated triterpenoid glycosides, were isolated from the roots of Ilex asprella. Their structures were determined on the basis of comprehensive spectroscopic analysis and chemical methods. Among these compounds, asprelloside B (2) and asprelloside C (3) are the first examples of triterpenoid glycosides bearing a rare 3,4-O-disulfo-xylopyranosyl residue. All the saponins isolated showed no significant effects against respiratory syncytial virus (RSV) and lipopolysaccharide-induced nitric oxide production in Raw264.7 macrophages.
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