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  • Title: Squamous cell carcinoma with perineural involvement in nevus sebaceus.
    Author: Locke ST, Schaffenburg WC, Breedlove JP, Davis Ii DW, Bowden Iii LP, Royer MC.
    Journal: Cutis; 2019 Apr; 103(4):E17-E19. PubMed ID: 31116824.
    Abstract:
    Nevus sebaceus (NS), also known as an organoid nevus, is a congenital skin hamartoma involving the pilosebaceous unit, epidermis, and adnexa, frequently occurring in the scalp area. During childhood, the lesion remains unchanged but may subsequently increase in size during puberty in response to hormonal release, with possible tumor development. We report a case of squamous cell carcinoma (SCC) development in an NS with histologic evidence of perineural involvement on the anterior central scalp of a 13-year-old adolescent girl. We also review the management and prognosis.
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