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  • Title: Chemical composition and larvicidal activity of the essential oil from the leaves of Onychopetalum periquino (Rusby) D.M. Johnson & N.A. Murray.
    Author: de Lima BR, da Silva FMA, Soares ER, de Almeida RA, Maciel JB, Fernandes CC, de Oliveira AC, Tadei WP, Koolen HHF, de Souza ADL, Pinheiro MLB.
    Journal: Nat Prod Res; 2021 Mar; 35(6):1038-1041. PubMed ID: 31135221.
    Abstract:
    The essential oil (EO) from the leaves of Onychopetalum periquino, obtained by hydrodistillation, was analyzed by gas chromatography coupled with mass spectrometry (GC-MS), and also was investigated for its larvicidal activity against Aedes aegypti larvae. Thirteen compounds, representing 91.31% of the crude oil, were identified. Major compounds were sesquiterpenes, including β-elemene (53.16%), spathulenol (11.94%) and β-selinene (9.25%). The EO showed high larvicidal activity with a lethal concentration (LC50) of 63.75 μg/mL and 100% mortality at 200 μg/mL. These results represent the first report about the chemical composition of O. periquino and the first larvicidal evaluation with Onychopetalum species.[Figure: see text].
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