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  • Title: A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata.
    Author: Lam SH, Jian SD, Hwang TL, Chen PJ, Hung HY, Kuo PC, Wu TS.
    Journal: Nat Prod Res; 2021 Jan; 35(1):17-24. PubMed ID: 31135226.
    Abstract:
    A new dimeric quaternary protoberberine alkaloid, bispalmatrubine (1), and thirteen known compounds (2-14) were purified from the tubers of Tinospora dentata. Their structures were determined by spectroscopic and spectrometric analytical methods. Among the isolates, eight compounds were examined for their in vitro anti-inflammatory potential and several tested alkaloids displayed moderate inhibitory effects of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
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