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  • Title: Crystallization and preliminary X-ray study of pig lens aldose reductase.
    Author: Rondeau JM, Samama JP, Samama B, Barth P, Moras D, Biellmann JF.
    Journal: J Mol Biol; 1987 Jun 20; 195(4):945-8. PubMed ID: 3116267.
    Abstract:
    Crystals of pig lens aldose reductase have been grown from polyethylene glycol solutions at pH 6.2 and analysed by X-ray diffraction. Two crystal forms were obtained. The first belongs to space group P1 with unit cell dimensions a = 81.3 A, b = 85.9 A, c = 56.6 A, alpha = 102.3 degrees, beta = 103.3 degrees, gamma = 79.0 degrees, with four molecules in the unit cell related by a 222 non-crystallographic symmetry. The second crystal form is hexagonal. The space group is P6(2)22 with a = b = 101 A, c = 257 A and two molecules in the asymmetric unit. Both forms are suitable for X-ray structure analysis to better than 3 A resolution.
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