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  • Title: Multiple tuberous and tendinous xanthomas diagnosed on fine-needle aspiration cytology-report of a rare case.
    Author: Tummidi S, Kothari K, Rojekar A, Tiwari A.
    Journal: Diagn Cytopathol; 2019 Sep; 47(9):939-942. PubMed ID: 31169968.
    Abstract:
    Xanthomas are papulonodular skin lesions present in lipoprotein metabolism disorders, which result in cholesterol deposits in subcutaneous tissue, tendons, ligaments, periosteum, etc. A 11-year-old male presented with multiple soft tissue swellings, prominently over joints. Fine-needle aspiration (FNA) from multiple sites had similar appearance with foamy histocytes and giant cells. Oil Red O and polarized microscopy were also positive for fat. We describe an unusual case of tendinous and tuberous xanthoma diagnosed by cytology. Acquaintance with fine-needle aspiration cytology findings in xanthomas can help to avoid the need of surgical biopsy, as xanthomas can regress on medical therapy alone.
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