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  • Title: Genetic polymorphisms in 16 X-STR loci analyzed in the She population from Zhejiang Province, China.
    Author: Yang Z, Chen C, Zhang J, Tao R, Xia R, Zhang X, Zhang J, Yu L, Zhang S, Li C.
    Journal: Leg Med (Tokyo); 2019 Jul; 39():25-28. PubMed ID: 31176892.
    Abstract:
    Allele frequencies for 16 X-chromosomal STR (X-STR) loci (DXS6795, DXS9902, DXS8378, HPRTB, GATA165B12, DXS7132, DXS7424, DXS6807, DXS6803, GATA172D05, DXS6800, DXS10134, GATA31E08, DXS6810, DXS6789, and DXS10159) were obtained from a sample set of 296 unrelated individuals from the Zhejiang She population in China. We observed a total of 117 alleles in the group, with allele frequencies ranging from 0.0022 to 0.8143. The most informative marker for the studied population was DXS10134, with a polymorphism information content (PIC) of 0.8547, and the least polymorphic locus was DXS6800 (PIC = 0.3071). The power of discrimination (PD) varied from 0.3244 (DXS6800) to 0.8680 (DXS10134) in males and from 0.5263 (DXS6800) to 0.9693 (DXS10134) in females. The combined PDM and PDF was 0.999999996987156 and 0.999999999999993, respectively. The combined MECD and MECT was 0.999993100252466 and 0.999999973583357, respectively. In the population comparisons, a close relationship between the Zhejiang She and Eastern Han populations was observed. In general, the present findings indicate that the 16 X-STR loci examined are highly genetically polymorphic in the She population of Zhejiang, providing useful information on She for forensic science and population genetic studies.
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