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  • Title: Successful treatment of metachronous contralateral intratubular germ cell neoplasia with partial orchiectomy and low-dose radiation in a patient previously treated for testicular carcinoma.
    Author: Schneller N, Grimes A, Muscal J, Quintanilla N, Mittal A, Paulino A, Foster J.
    Journal: Pediatr Blood Cancer; 2019 Oct; 66(10):e27872. PubMed ID: 31179623.
    Abstract:
    Intratubular germ cell neoplasia (ITGCN) of the testis is a precursor to testicular germ cell tumor (TGCT), which can lead to the development of invasive cancer. In patients with a history of previously treated unilateral TGCT, treatment for ITGCN of the contralateral testis needs to be balanced with the risks of subsequent infertility. Here, we present a 17- year- old patient with ITGCN diagnosed after treatment of contralateral nonseminomatous TGCT who was successfully treated with a partial orchiectomy followed by low-dose radiation with preservation of his testosterone production.
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