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  • Title: Trabecular bone score of postmenopausal women is positively correlated with bone mineral density and negatively correlated with age and body mass index.
    Author: Torgutalp ŞŞ, Babayeva N, Kara ÖS, Özkan Ö, Dönmez G, Korkusuz F.
    Journal: Menopause; 2019 Oct; 26(10):1166-1170. PubMed ID: 31188287.
    Abstract:
    OBJECTIVE: Trabecular bone score (TBS), an indirect evaluation of skeletal microarchitecture, is calculated from dual-energy X-ray absorptiometry (DXA). This study aimed to determine the mean TBS values in healthy postmenopausal women and overall association between TBS and demographic features, bone mineral density (BMD) of the lumbar spine and femoral neck, and BMD to body mass index (BMI) ratio of the lumbar spine. METHODS: Fifty-three postmenopausal healthy women were enrolled. The BMD of the lumbar spine and femoral neck was measured by DXA. Anteroposterior lumbar spine acquisitions were used to calculate the TBS for L1 to L4. RESULTS: The mean BMD of the lumbar spine and femoral neck was 0.945 ± 0.133 and 0.785 ± 0.112 g/cm, respectively. The mean TBS was 1.354 ± 0.107. There was a significant positive moderate correlation between TBS and total lumbar BMD to BMI ratio (r = 0.595, P < 0.001), and significant positive weak correlations between TBS and BMD of the lumbar spine (r = 0.347, P = 0.011) as well as between TBS and femoral neck (r = 0.305, P = 0.026), whereas significant negative moderate correlations were observed between TBS and age (r = -0.393, P = 0.004) as well as between TBS and BMI (r = -0.333, P = 0.015). CONCLUSIONS: TBS values of postmenopausal women were negatively correlated with age and BMI, and positively with BMD and BMD to BMI ratio.
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