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  • Title: Studies on the influence of thiols on lymphocytes (T-type lymphocytes) functions.
    Author: Krzystyniak K, Ryzewski J, Chwaliński S.
    Journal: Arch Immunol Ther Exp (Warsz); 1978; 26(1-6):367-70. PubMed ID: 312073.
    Abstract:
    We described changes in nonprotein sulfhydryl content and in intracellular concentration of cysteine (unbound form) in lymphocytes incubated with cysteine, cysteine hydrazide and D-penicillamine (dimethy lcysteine) in concentrations which do not alter the viability of the cells. Essential differences between the action of cysteine and cysteine hydrazide on one hand, and D-penicillamine on the other, can be observed. The formers cause the argumentation in nonprotein thiols content in lymphocytes, whereas D-penicillamine in a similar concentration does hardly alters the intracellular redox -SH/SS potential of nonprotein thiols within the lymphocytes.
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