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  • Title: Maternal and neonatal responses to alfentanil administered before induction of general anaesthesia for caesarean section.
    Author: Dann WL, Hutchinson A, Cartwright DP.
    Journal: Br J Anaesth; 1987 Nov; 59(11):1392-6. PubMed ID: 3120764.
    Abstract:
    The cardiovascular response to tracheal intubation was compared in two groups of patients undergoing elective Caesarean section. Both groups received a standard technique of general anaesthesia. One of the groups received alfentanil 10 micrograms kg-1 1 min before induction of anaesthesia, the other acted as a control group. In the alfentanil group there was a significant modification of the cardiovascular response to intubation as compared with the control group (P less than 0.01). No adverse effect on the neonate was seen. However, a significant increase in the incidence of postoperative nausea occurred in mothers in the alfentanil group (P less than 0.05).
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