These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Centrally administered leumorphin possesses potent depressor activity in conscious rats.
    Author: Itoh H, Nakao K, Yamada T, Morii N, Shiono S, Sakamoto M, Sugawara A, Saito Y, Katsuura G, Shiomi T.
    Journal: NIDA Res Monogr; 1986; 75():512-5. PubMed ID: 3123970.
    Abstract:
    The effect of intracerebroventricular (i.c.v.) administration of leumorphin on basal blood pressure and angiotensin II (AII)-stimulated increase in blood pressure was examined in conscious unrestrained rats. The i.c.v. injection of leumorphin (0.06 and 0.6 nmol) elicited significant depressor effect. The i.c.v. administration of leumorphin with AII (0.1 nmol) significantly attenuated the AII-induced pressor response and, furthermore, lowered blood pressure below the basal level. These results suggest that leumorphin is involved in the central control of blood pressure.
    [Abstract] [Full Text] [Related] [New Search]