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  • Title: Effects of rokitamycin and other macrolide antibiotics on Mycoplasma pneumoniae in L cells.
    Author: Misu T, Arai S, Furukawa M, Yamamoto Y, Miyazaki T.
    Journal: Antimicrob Agents Chemother; 1987 Nov; 31(11):1843-5. PubMed ID: 3124740.
    Abstract:
    Fifty strains of Mycoplasma pneumoniae in L cells were tested for susceptibility to macrolide antibiotics. Rokitamycin, a new macrolide antibiotic, was most active against these organisms, with an MIC for 90% of strains of 0.007 microgram/ml. The MICs of erythromycin, josamycin, and kitasamycin for 90% of strains were 0.03, 0.03, and greater than or equal to 0.06 microgram/ml, respectively. Based on these results, rokitamycin is a promising antibiotic for the treatment of mycoplasmal infections, and further clinical investigations are needed.
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