These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A nanowell-based molecularly imprinted electrochemical sensor for highly sensitive and selective detection of 17β-estradiol in food samples.
    Author: Wen T, Wang M, Luo M, Yu N, Xiong H, Peng H.
    Journal: Food Chem; 2019 Nov 01; 297():124968. PubMed ID: 31253322.
    Abstract:
    A novel electrochemical sensor was developed combination molecularly imprinted polymers (MIPs) with nanowell technology, and which was utilized for sensitive and selective 17β-estradiol (17β-E2) detection. A nanowell gold film with a thickness of 120 nm and a pore size of ∼20 nm was immobilized onto gold electrode surface to form a nanowell-based electrode. MIPs was then synthesized onto the nanowell-based electrode using electro-polymerization method, and then the nanowell-based MIP electrochemical sensor was formed. This sensor surface exhibited 3D-nanowell structure with higher surface area and enhanced electron-transport ability, while MIPs afford stronger recognition capability with higher selectivity and specificity. Most importantly, the developed sensor was validated for 17β-E2 detection in food samples with larger detection range from 1 × 10-12 to 1 × 10-5 and lower detection limit of 1 × 10-13. Therefore, such nanowell-based MIP electrochemical sensor may be a promising candidate electrochemical sensor for trace pollution detection in food samples.
    [Abstract] [Full Text] [Related] [New Search]