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  • Title: Choroidal Changes at the Leakage Site in Acute Central Serous Chorioretinopathy.
    Author: Sahoo NK, Maltsev DS, Goud A, Kulikov AN, Chhablani J.
    Journal: Semin Ophthalmol; 2019; 34(5):380-385. PubMed ID: 31257974.
    Abstract:
    Purpose: To analyze the choroidal vasculature at leak site and at the center of macula in acute central serous chorioretinopathy (CSCR) and to evaluate their co-relation with eccentricity of leak site. Methods: This retrospective study involved optical coherence tomography analysis of 27 eyes with acute CSCR. Relationship between macular thickness; large choroidal vessels diameter; baseline subfoveal and leakage point choroidal thickness, and eccentricity of leak point was evaluated. Results: A larger choroidal vessel caliber/choroidal thickness ratio was found at the leak site than fovea in both active (p = 0.0001) and resolved (p = 0.003) CSCR. Ratio at leakage point decreased after resolution of SRF (p = 0.004). Choroidal thickness at subfovea (p = 0.004), leakage point (p = 0.02); and difference between central and leakage point choroidal thickness (r = 0.6, p = 0.009) were significantly associated with the eccentricity of leakage point. Conclusion: Subfoveal and leak site choroidal profile could predict the eccentricity of leakage in CSCR.
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