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  • Title: Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Örebro County, Sweden, May 2019.
    Author: Unemo M, Hansen M, Hadad R, Lindroth Y, Fredlund H, Puolakkainen M, Sundqvist M.
    Journal: Euro Surveill; 2019 Jun; 24(26):. PubMed ID: 31266590.
    Abstract:
    We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Örebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential.
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