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  • Title: [Release of thyrotropin releasing hormone (TRH) from human prolactin-secreting pituitary adenoma cells. Modulation by dopamine].
    Author: Le Dafniet M, Blumberg-Tick J, Yuan Li J, Brandi AM, Bression D, Barret A, Feinstein MC, Peillon F.
    Journal: C R Acad Sci III; 1988; 306(3):129-34. PubMed ID: 3126991.
    Abstract:
    We found, by radioimmunoassay, that thyrotropin-releasing-hormone (TRH) was present in human prolactin (PRL)-secreting adenomas (mean: 89 +/- 45 (SEM) fmol/mg proteins) and was released by perifused adenomatous cells at levels varying from 5 to 60 fmol/10(6) cell/2 min. TRH release was increased in the presence of dopamine (DA) 10(-6) M but was not modified by the presence of somatostatin (SRIH) 10(-6) M.
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