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  • Title: An epidemiological investigation associating aflatoxin M1 with milk production in dairy cattle.
    Author: Corbett WT, Brownie CF, Hagler SB, Hagler WM.
    Journal: Vet Hum Toxicol; 1988 Feb; 30(1):5-8. PubMed ID: 3127990.
    Abstract:
    An attempt was made to utilize the analysis for aflatoxin M2 in milk, instead of aflatoxin B1 in feed for a pilot epidemiological study addressing the association of M1 levels and various production parameters. Four dairy farms, representing above average to below average management practices, were identified with 10 animals being randomly selected from each farm for this study. Milk samples and production data were evaluated from these animals in order to gain insight into the possible effects of low level mycotoxin ingestion on production and to test whether or not this approach offered potential for future epidemiological studies. Feed samples were basically negative for the presence of aflatoxin B1, yet milk analysis revealed the presence of M1 in a large percentage of the animals. Further, the M1 levels appeared to be associated with a decrease in daily milk production. This study indicates that employing M1 analysis in milk for epidemiological investigations of low level mycotoxin ingestion effects, instead of B1 feed analysis, is feasible and offers a potential for more definitive studies in this area.
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