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  • Title: Studies on the biosynthesis of beta-amino acids, the lipid moiety of iturins A, in Bacillus subtilis.
    Author: Hourdou ML, Besson F, Michel G.
    Journal: J Antibiot (Tokyo); 1988 Feb; 41(2):207-11. PubMed ID: 3128514.
    Abstract:
    The biosynthesis of the beta-amino acid components of iturins A was studied in comparison to the biosynthesis of fatty acids. Palmitic acid was incorporated into the lipid moiety of iturins A when it was added to the culture medium of the iturin producer Bacillus subtilis. Addition of unlabeled palmitic acid enhanced the formation of straight-chain beta-amino acids and addition of valine or leucine increased the production of branched beta-amino acids. These modifications correlated with modifications in the corresponding biosynthesized fatty acids.
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