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  • Title: Transcriptional regulation of the proC gene of Salmonella typhimurium.
    Author: Brady RA, Csonka LN.
    Journal: J Bacteriol; 1988 May; 170(5):2379-82. PubMed ID: 3129409.
    Abstract:
    We found that the expression of beta-galactosidase in Salmonella typhimurium strains carrying proC-lacZ fusions was neither repressed by excess proline nor derepressed by proline limitation. Except for a three- to fourfold decrease in the beta-galactosidase specific activity under conditions causing a severely reduced growth rate, the expression of the proC-lacZ fusions was nearly invariant under a variety of culture conditions. Thus, the proC gene is unlike most other amino acid biosynthetic genes in that its expression is nearly constitutive.
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