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  • Title: Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with Hodgkin's disease.
    Author: Rubinstein A, Ghossein NA, Melamed J, Bosworth JL, Murphy RA.
    Journal: Oncology; 1979; 36(1):23-6. PubMed ID: 313034.
    Abstract:
    Various immunological parameters were evaluated in untreated Hodgkin's patients before and after sensitization with dinitrochlorobenzene (DNCB). The ratio (r) of these parameters after/before DNCB sensitization for patients and second/first samples in the controls were calculated. There were significantly more patients in the r greater than 1.1 group for PHA and Con A responses and for peripheral blood T cell percentages. These data suggest that DNCB sensitization may have a nonspecific immunopotentiation effect.
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