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  • Title: [The advance of materials for preventing adhesion in tympanoplasty].
    Author: Wei XM, Feng GD, Gao ZQ.
    Journal: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2019 Jul 07; 54(7):550-553. PubMed ID: 31315367.
    Abstract:
    For otitis media patients with severe mucosal lesions, adhesion is the most common poor prognosis of tympanoplasty. We generally consider tympanic cavity adhesion is due to eustachian tube dysfunction and poor middle ear ventilation. The mechanism of adhesion is unclear so far, which we thought is mainly associated with wounded surface and activation of the fibrinolytic system. To solve the problem of adhesion, several materials have been used in the middle ear surgery, such as plastic sheet, silicone sheet and absorbable material. And there are some benefits. The most widely used is silicone sheet, and there are some researches focused on its thickness, shape and components to achieve better anti-adhesion effect. In this article, we will do a review for the research advances of anti-adhesion materials in tympanoplasty. 鼓室成形术后鼓室粘连是中耳黏膜病变严重的中耳炎患者预后不佳的常见原因。通常认为鼓室粘连是咽鼓管功能障碍、中耳通气不佳所致，粘连的发生机制至今不明，主要认为与创面的产生和纤溶系统的激活有关。为解决这一问题，多种防粘连材料曾被应用于中耳手术，取得了一定的效果，主要包括塑料制品、硅胶制品和可吸收材料。其中硅胶制品应用最为广泛，先后有学者在其厚度、形状及成分上做了改良和探索，以求达到更好的防粘连效果。本文就鼓室成形术中预防粘连的植入材料的研究进展做一综述。.
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