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  • Title: Calodioscurins A and B, two new isoprenylated xanthones from the stem bark of Calophyllum dioscurii P.F. Stevens.
    Author: Tjahjandarie TS, Tanjung M, Rahmania DF, Rhidoma CI, Saputri RD.
    Journal: Nat Prod Res; 2021 Apr; 35(7):1153-1158. PubMed ID: 31328544.
    Abstract:
    Two new isoprenylated xanthones, calodioscurin A (1) and B (2) were isolated from the stem bark of Calophyllum dioscurii P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide (3) and methyl inophyllum P (4). The structures of two new compounds were determined based on their HRESIMS, IR, UV, 1D and 2D NMR spectral data. Compounds 1-4 were assayed on P-388 cells, compound 2 showed IC50 value 11.5 μM and categorised moderate activity.
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