These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres.
    Author: Kaya K, Kusumi T.
    Journal: Biochim Biophys Acta; 1988 Jun 15; 960(3):303-8. PubMed ID: 3132980.
    Abstract:
    A diacyltaurolipid was found in cells of Tetrahymena mimbres (formerly Tetrahymenas pyriformis NT-1). The lipid accounted for about 0.05% of the total lipids of the cells, and was composed of taurine (1 equiv.), 3,7,13-trihydroxystearic acid (1 equiv.) and non-hydroxy fatty acids (2 equiv.). By mild alkaline hydrolysis, non-hydroxy fatty acids (2 equiv.) and 2-(3,7,13-trihydroxyoctadecanoyl)aminoethanesulfonic acid were obtained. For determination of the positions of the ester bonds of the lipid, the free hydroxy group of the intact lipid was converted to a ketone, and the esterified hydroxy groups were acetylated after methanolic hydrochloric acid hydrolysis. By mass and nuclear magnetic resonance spectrometry, the structure of the derivative was identified as methyl 3,7-diacetoxy-13-oxooctadecanoate. From these results, the diacyltaurolipid isolated from T. mimbres was identified as 2-(3,7-diacyloxy-13-hydroxyoctadecanoyl)aminoethanesulfonic acid (7-acyltaurolipid A). This structure suggests that the diacyltaurolipid may be formed by acylation of taurolipid A.
    [Abstract] [Full Text] [Related] [New Search]