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  • Title: Prevention of non-specific bronchial hyperreactivity. Dose-dependent effect of sodium cromoglycate metered dose aerosol.
    Author: Del Bufalo D, Fasano L, Patalano F, Ruggieri F, Gunella G.
    Journal: Allergol Immunopathol (Madr); 1988; 16(2):77-80. PubMed ID: 3134808.
    Abstract:
    The protective effect of different doses of sodium cromoglycate (4 mg, 12 mg and 20 mg) given as pressurized aerosol on fog-induced bronchoconstriction were investigated in three different groups of asthmatic patients. Premedication with the active drug was compared versus absence of premedication. The authors discuss their results by a statistical analysis of the FEV1 variations. Sodium cromoglycate effectively prevents fog-induced bronchoconstriction with a clear dose-dependent effect.
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